Joined in 2023 
82 
63 About this deal
The following undesirable effects detailed in Table 1 are nicotine related adverse events for all oral dosage forms.
It’s also possible to overdose on nicotine when you’re using any form of nicotine replacement therapy. Overdose symptoms include: Tell all of your health care providers that you take this medicine (nicotine lozenges). This includes your doctors, nurses, pharmacists, and dentists. Smoking during pregnancy is associated with risks such as intra-uterine growth retardation, premature birth or stillbirth. Stopping smoking is the single most effective intervention for improving the health of both the pregnant smoker and her baby. The earlier abstinence is achieved the better. Nicotine passes to the foetus and affects its breathing movements and circulation. The effect on the circulation is dose-dependent.
What are some other side effects of Nicotine Lozenges?
Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that may be associated with Nicotinell lozenges. Just because a side effect is stated here doesn't mean that all people using Nicotinell lozenges will experience that or any side effect. Common side effects (affect between 1 in 10 and 1 in 100 people) Danger in small children: doses of nicotine that are tolerated by adult smokers during treatment may produce severe symptoms of poisoning in small children and may prove fatal (please see Section 4.9). WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Tell your If you know you might have issues controlling your nicotine intake via either lozenge or gum, you might want to think about using the patch instead. Ideally, if you're pregnant or breastfeeding you should give up smoking without using nicotine replacement therapy.
People with a peptic ulcer or inflammation of the stomach lining (gastritis), foodpipe ( oesophagitis), or mouth and throat. Swallowed nicotine can aggravate these conditions. The plasma concentrations of other active substances metabolised by CYP1A2 e.g. caffeine, paracetamol, phenazone, phenylbutazone, pentazocine, lidocaine, benzodiazepines, warfarin, oestrogen and vitamin B12 may also increase. However, the clinical significance of this effect for these active substances is unknown. More than 20 metabolites have been identified, all believed to be less active than nicotine. The main metabolite is cotinine which has a half-life of 15-20 hours and with approximately 10 times higher plasma concentration than nicotine. Nicotine's plasma-protein binding is less than 5%. Changes in nicotine binding from the use of concomitant medicinal products or due to altered disease state are not expected to have significant effect on nicotine kinetics. The main metabolite in urine is cotinine (15% of the dose) and trans-3-hydroxy cotinine (45% of the dose). Cold sores may develop in connection with smoking cessation, but any relation with the nicotine treatment is unclear. If you still smoke, chew tobacco, or use other products that have nicotine while using this medicine (nicotine lozenges).
Already a customer?
Distribution volume after intravenous administration of nicotine is approximately 2-3 1/kg and the half- life is 2 hours. Nicotine is metabolised principally in the liver and the plasma clearance is approximately 1.2 l/min; nicotine also metabolises in the kidney and lungs. Nicotine crosses the blood-brain barrier. Excessive consumption of lozenges by subjects who have not been in the habit of inhaling tobacco smoke, could possibly lead to nausea, faintness and headache.
If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was
Signs and symptoms of an overdose from nicotine lozenge would be expected to be the same as those of acute nicotine poisoning, including: weakness, perspiration, pallor, hyperhidrosis, salivation, throat burn, nausea, vomiting, diarrhoea, abdominal pain, hearing and visual disturbances (sensory disturbance), headache, tachycardia and cardiac arrhythmia, dyspnoea, dizziness, tremor, confusional state and asthenia. Prostration, hypotension, circulatory collapse, coma, respiratory failure, and terminal convulsions may ensue with large overdoses. Table 1 shows events which were identified from a double-blind, randomised, placebo-controlled lozenge clinical study involving 1818 patients. Adverse events reported in this study have been considered for inclusion, where the incidence in the 2 mg or 4 mg nicotine arm was higher than the corresponding placebo arm. Frequencies are calculated from safety data of the study. However, if you're pregnant and can't stop smoking using willpower alone, you can use Nicotinell lozenges to help you. This will be safer for you and your baby than continuing to smoke. The lozenges deliver less nicotine (and none of the other potentially disease-causing agents) than would be obtained from cigarettes. However, you should aim to stop using Nicotinell lozenges as soon as possible, preferably after two to three months, because nicotine in any form has been shown to adversely affect the development of the baby, both in the womb and after birth. You can get more advice from your doctor or pharmacist. Adverse reactions are listed below, by system organ class and frequency. Frequencies are defined as:
Related:
Great Deal 
New Comment